Reverse signaling by FasL inhibits primary human T cell activation
Authors: M Paulsen, S Valentin and O Janssen
Citation: Cell Communication and Signaling 2009 7(Suppl 1):A23
Content type: Meeting abstract Published on: 26 February 2009
This article is part of a Supplement: Volume 7 Supplement 1
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Correction: Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling
Authors: Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski and Lukasz Opalinski
Citation: Cell Communication and Signaling 2023 21:129
Content type: Correction Published on: 13 June 2023
The original article was published in Cell Communication and Signaling 2023 21:122
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Growth factor signaling – cell biology turned into medicine
Authors: A Östman
Citation: Cell Communication and Signaling 2009 7(Suppl 1):A22
Content type: Meeting abstract Published on: 26 February 2009
This article is part of a Supplement: Volume 7 Supplement 1
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Early beginnings - the emergence of complex signaling systems and cell-to-cell communication
Authors: Stephan M Feller
Citation: Cell Communication and Signaling 2010 8:16
Content type: Editorial Published on: 12 July 2010
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Nucleoplasmic calcium signaling and cell proliferation: calcium signaling in the nucleus
Calcium (Ca2+) is an essential signal transduction element involved in the regulation of ... is required at various key stages of the cell cycle. Intracellular Ca2+ is crucial for the orderly cell cycle progressi...
Authors: Rodrigo R Resende, Lidia M Andrade, Andre G Oliveira, Erika S Guimarães, Silvia Guatimosim and M Fatima Leite
Citation: Cell Communication and Signaling 2013 11:14
Content type: Review Published on: 21 February 2013
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First Honorary Medal of the Signal Transduction Society (STS) and 'CELL COMMUNICATION AND SIGNALING' awarded to Professor Anthony J. (Tony) Pawson
Authors: Stephan M Feller
Citation: Cell Communication and Signaling 2011 9:3
Content type: Editorial Published on: 19 January 2011
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Cell Communication and Signaling is becoming the official journal of the Signal Transduction Society
Authors: Stephan M Feller, Ralf Hass, Ottmar Janssen and Karlheinz Friedrich
Citation: Cell Communication and Signaling 2008 6:1
Content type: Editorial Published on: 6 August 2008
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Excellence in cell signaling research recognized with major new award
The newly installed Life Sciences Breakthrough Prize (http://www.breakthroughprizeinlifesciences.org/...), which comes with more than double the financial re...
Authors: Stephan M Feller
Citation: Cell Communication and Signaling 2013 11:17
Content type: Editorial Published on: 4 March 2013
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Tony (Anthony James) Pawson, a giant in the field of cell signaling research, dies unexpectedly at the age of 60
Tony was widely recognized as a world leader in the field of signal transduction and conducted seminal work especially on signaling processes related to protein – protein interactions and cancers. He will be m...
Authors: Stephan M Feller
Citation: Cell Communication and Signaling 2013 11:61
Content type: Obituary Published on: 19 August 2013
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Erratum to: The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells
Authors: Hui Cai and Yan Xu
Citation: Cell Communication and Signaling 2013 11:92
Content type: Erratum Published on: 13 December 2013
The original article was published in Cell Communication and Signaling 2013 11:31
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Role of cell rearrangement and related signaling pathways in the dynamic process of tip cell selection
Angiogenesis is a complex, highly-coordinated and multi-step process of new blood vessel formation from pre-existing blood vessels. When initiated, the sprouting process is spearheaded by the specialized endothel...
Authors: Yaru Guo, Shihan Zhang, Dandan Wang, Boon Chin Heng and Xuliang Deng
Citation: Cell Communication and Signaling 2024 22:24
Content type: Review Published on: 9 January 2024
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Cell-to-cell signaling through light: just a ghost of chance?
Despite the large number of reports attributing the signaling between detached cell cultures to the electromagnetic phenomena, almost no ... a rigorous analysis of the possibility of such signaling.
Authors: Ondřej Kučera and Michal Cifra
Citation: Cell Communication and Signaling 2013 11:87
Content type: Debate Published on: 12 November 2013
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Intrinsically disordered proteins play diverse roles in cell signaling
Signaling pathways allow cells to detect and respond to a wide...2+...or chemokine proteins) and physical stimuli (e.g., sheer stress, light). Together, these pathways form an extensive communication network that...
Authors: Sarah E. Bondos, A. Keith Dunker and Vladimir N. Uversky
Citation: Cell Communication and Signaling 2022 20:20
Content type: Review Published on: 17 February 2022
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HIV-1 Nef: a multifaceted modulator of T cell receptor signaling
Nef, an accessory protein of the Human Immunodeficiency Virus type 1 (HIV-1), is dispensable for viral replication in cell culture, but promotes virus replication and pathogenesis ... adaptor, HIV-1 Nef modulates...
Authors: Libin Abraham and Oliver T Fackler
Citation: Cell Communication and Signaling 2012 10:39
Content type: Review Published on: 10 December 2012
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Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Gα in live cells
We employed a bioluminescence resonance energy transfer technique and confocal microscopy to examine potential interactions among PAR4, RGS, and Gα subunits. The inhibitory effects of RGS proteins on PAR4-mediate...
Authors: Yukeyoung Kim and Sungho Ghil
Citation: Cell Communication and Signaling 2020 18:86
Content type: Research Published on: 9 June 2020
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Calcium mediated functional interplay between myocardial cells upon laser-induced single-cell injury: an in vitro study of cardiac cell death signaling mechanisms
The electromechanical function of myocardial tissue depends on the intercellular communication between cardiomyocytes (CMs) as well as their crosstalk with other cell types. Cell injury, and subsequent death trig...
Authors: Krishna Chander Sridhar, Nils Hersch, Georg Dreissen, Rudolf Merkel and Bernd Hoffmann
Citation: Cell Communication and Signaling 2020 18:191
Content type: Research Published on: 28 December 2020
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Mast cell exosomes promote lung adenocarcinoma cell proliferation – role of KIT-stem cell factor signaling
Exosomes were isolated from the human mast cell line, HMC-1, and uptake of PKH67-labelled exosomes by the lung epithelial cell line, A549, was examined using flow...c-KIT...mRNA was determined by RT-PCR. The cell
Authors: Hui Xiao, Cecilia Lässer, Ganesh Vilas Shelke, Juan Wang, Madeleine Rådinger, Taral Rameshchand Lunavat, Carina Malmhäll, Li Hui Lin, Jia Li, Li Li and Jan Lötvall
Citation: Cell Communication and Signaling 2014 12:64
Content type: Research Published on: 14 October 2014
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Tfg (Trk fused gene) is a Carma-1/IKKγ interacting protein involved in CD40-induced canonical NF-κB signaling
Authors: M Grohmann, I Hermann, M Hampel, M Karas, H Kalbacher, HM Jäck and D Mielenz
Citation: Cell Communication and Signaling 2009 7(Suppl 1):A4
Content type: Meeting abstract Published on: 26 February 2009
This article is part of a Supplement: Volume 7 Supplement 1
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Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal
The latent membrane protein (LMP) 2A of Epstein-Barr virus (EBV) is expressed during different latency stages of EBV-infected B cells in which it triggers activation of cytoplasmic...2+...concentration similar to...
Authors: Niklas Engels, Gökhan Yigit, Christoph H Emmerich, Dirk Czesnik, Detlev Schild and Jürgen Wienands
Citation: Cell Communication and Signaling 2012 10:9
Content type: Research Published on: 3 April 2012
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Acute myeloid leukemia-derived exosomes deliver miR-24-3p to hinder the T-cell immune response through DENN/MADD targeting in the NF-κB signaling pathways
We found that AML blast-released EXOs enhance CD3 T-cell apoptosis in both CD4 and CD8 T cells. We hypothesized that miRNAs present in EXOs ... in mediating the changes observed in AML T-cell survival. We found t...
Authors: Khalid Otmani, Redouane Rouas, Laurence Lagneaux, Mohammad Krayem, Hugues Duvillier, Mimoune Berehab and Philippe Lewalle
Citation: Cell Communication and Signaling 2023 21:253
Content type: Research Published on: 21 September 2023
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The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling
T-cell membrane scaffold proteins are pivotal in T cell function, acting as versatile signaling hubs. While CD6 forms a large intracellular ... well-characterized ligand expressed on most antigen-presenting cells
Authors: Rita F. Santos, Annika de Sousa Linhares, Peter Steinberger, Simon. J. Davis, Liliana Oliveira and Alexandre M. Carmo
Citation: Cell Communication and Signaling 2024 22:286
Content type: Research Published on: 24 May 2024
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The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation
Aberrant activation of the Hedgehog (Hh) signaling pathway is frequently observed in hepatocellular carcinoma ... a key oncofetal transcription factor and a master cell cycle regulator. Targeting protein for Xeno...
Authors: Yiting Wang, Hailong Wang, Zhengwei Yan, Guohua Li, Guohui Hu, Hong Zhang, Dengliang Huang, Yao Wang, Xiang Zhang, Yehong Yan, Quqin Lu, Minzhang Cheng and Shiwen Luo
Citation: Cell Communication and Signaling 2020 18:116
Content type: Research Published on: 28 July 2020
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Crosstalk between KDEL receptor and EGF receptor mediates cell proliferation and migration via STAT3 signaling
Hostile microenvironment of cancer cells provoke a stressful condition for endoplasmic reticulum ... KDEL receptor (KDELR), is required for cell proliferation and migration induced by secreted chaperones. ... , i...
Authors: Jie Jia, Lianhui Zhu, Xihua Yue, Shuocheng Tang, Shuaiyang Jing, Chuanting Tan, Yulei Du, Jingkai Gao, Intaek Lee and Yi Qian
Citation: Cell Communication and Signaling 2024 22:140
Content type: Research Published on: 20 February 2024
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Characterization of two distinct immortalized endothelial cell lines, EA.hy926 and HMEC-1, for in vitro studies: exploring the impact of calcium electroporation, Ca2+ signaling and transcriptomic profiles
Disruption of Ca2+ homeostasis after calcium electroporation (CaEP) in tumors has been shown to elicit an enhanced antitumor effect with varying impacts on healthy tissue, such as endothelium. Therefore, our stud...
Authors: Barbara Lisec, Tim Bozic, Iva Santek, Bostjan Markelc, Milka Vrecl, Robert Frangez and Maja Cemazar
Citation: Cell Communication and Signaling 2024 22:118
Content type: Research Published on: 12 February 2024
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miR-1250-5p is a novel tumor suppressive intronic miRNA hypermethylated in non-Hodgkin’s lymphoma: novel targets with impact on ERK signaling and cell migration
...miR-1250-5p is a novel tumor suppressive intronic miRNA co-regulated and silenced by promoter DNA methylation of its host gene AATK in NHL. MAPK1 and WDR1 are novel miR-1250-5p direct targets rendering inhibit...
Authors: Min Yue Zhang, Lu Qian Wang and Chor Sang Chim
Citation: Cell Communication and Signaling 2021 19:62
Content type: Research Published on: 27 May 2021
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AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation
The CARMA1-BCL10-MALT1 (CBM) complex bridges T cell receptor (TCR) signaling to the canonical IκB kinase (IKK)/ ... -κB pathway. The CBM complex constitutes a signaling cluster of more than 1 Mio Dalton....
Authors: Gisela Schimmack, Andrea C Eitelhuber, Michelle Vincendeau, Katrin Demski, Hisaaki Shinohara, Tomohiro Kurosaki and Daniel Krappmann
Citation: Cell Communication and Signaling 2014 12:49
Content type: Short report Published on: 22 July 2014
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Identification of myoferlin as a mitochondria-associated membranes component required for calcium signaling in PDAC cell lines
Pancreatic ductal adenocarcinoma is an aggressive cancer type with one of the lowest survival rates due to late diagnosis and the absence of effective treatments. A better understanding of PDAC biology will he...
Authors: Sandy Anania, Martin Farnir, Raphaël Peiffer, Yasmine Boumahd, Marc Thiry, Ferman Agirman, Naima Maloujahmoum, Akeila Bellahcène and Olivier Peulen
Citation: Cell Communication and Signaling 2024 22:133
Content type: Research Published on: 17 February 2024
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CPNE1 promotes non-small cell lung cancer progression by interacting with RACK1 via the MET signaling pathway
We found that CPNE1 facilitates tumorigenesis in NSCLC by interacting with RACK1, which further induces activation of MET signaling. CPNE1 overexpression promoted cell proliferation, migration, invasion and MET signaling
Authors: Anqi Wang, Wen Yang, Yue Li, Yang Zhang, Jieqi Zhou, Ruochen Zhang, Weijie Zhang, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu and Jian-an Huang
Citation: Cell Communication and Signaling 2022 20:16
Content type: Research Published on: 31 January 2022
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The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion
Long non-coding RNAs (lncRNAs) regulate cellular processes by interacting with RNAs or proteins. Transforming growth factor β (TGFβ) signaling via Smad proteins regulates gene networks that control diverse biolog...
Authors: Caroline Gélabert, Panagiotis Papoutsoglou, Irene Golán, Eric Ahlström, Adam Ameur, Carl-Henrik Heldin, Laia Caja and Aristidis Moustakas
Citation: Cell Communication and Signaling 2023 21:271
Content type: Research Published on: 2 October 2023
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LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
G protein-coupled receptor heteromerization is believed to exert dynamic regulatory impact on signal transduction. CXC chemokine receptor 4 (CXCR4)...1) is implicated in cancer cell proliferation and migration. I...
Authors: Jong Min Hong, Jin-Woo Lee, Dong-Seung Seen, Jae-Yeon Jeong and Won-Ki Huh
Citation: Cell Communication and Signaling 2023 21:257
Content type: Research Published on: 25 September 2023
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The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect
Endothelial progenitor cells (EPCs) are non-differentiated endothelial cells (ECs) present in blood circulation that are involved in neo-vascularization and correction of damaged endothelial sites. Since EPCs ...
Authors: Sina Naserian, Mohamed Essameldin Abdelgawad, Mazdak Afshar Bakshloo, Guillaume Ha, Nassim Arouche, José L. Cohen, Benoît L. Salomon and Georges Uzan
Citation: Cell Communication and Signaling 2020 18:94
Content type: Research Published on: 16 June 2020
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CLPTM1L induces estrogen receptor β signaling-mediated radioresistance in non-small cell lung cancer cells
Radioresistance is a major challenge in lung cancer radiotherapy, and new radiosensitizers are urgently needed. Estrogen receptor β (ERβ) is involved in the progression of non-small cell lung cancer (NSCLC), h...
Authors: Hang Li, Jun Che, Mian Jiang, Ming Cui, Guoxing Feng, Jiali Dong, Shuqin Zhang, Lu Lu, Weili Liu and Saijun Fan
Citation: Cell Communication and Signaling 2020 18:152
Content type: Research Published on: 17 September 2020
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Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH l...
Authors: Xue-min Gao, Jian Li and Xin-xin Cao
Citation: Cell Communication and Signaling 2022 20:195
Content type: Review Published on: 19 December 2022
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Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo
One of the most insidious characteristics of cancer is its spread to and ability to compromise distant organs via the complex process of metastasis. Communication between cancer cells and organ-resident cells ...
Authors: Alexandra Koch, Shashank Saran, Doan Duy Hai Tran, Sabine Klebba-Färber, Hauke Thiesler, Katherina Sewald, Susann Schindler, Armin Braun, Robert Klopfleisch and Teruko Tamura
Citation: Cell Communication and Signaling 2014 12:73
Content type: Methodology Published on: 7 November 2014
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Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture
Uterine leiomyomas (fibroids) are benign smooth muscle tumors that often contain an excessive extracellular matrix (ECM). In the present study, we investigated the interactions between human uterine leiomyoma ...
Authors: Alicia B Moore, Linda Yu, Carol D Swartz, Xaiolin Zheng, Lu Wang, Lysandra Castro, Grace E Kissling, David K Walmer, Stanley J Robboy and Darlene Dixon
Citation: Cell Communication and Signaling 2010 8:10
Content type: Research Published on: 10 June 2010
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GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment
The effects of G protein-coupled receptor 65 (GPR65) on cell adhesion and other cellular functions were tested ... spheroids, mouse blastocysts, and HTR-8/SVneo cells. Specifically, we employed HTR-8/SVneo cells ...
Authors: Jia Mao, Ying Feng, Yayun Zheng, Yaqiu Gao, Linyu Zhang, Xinrui Sun, Yilun Wu, Xiaofeng Zhu and Fang Ma
Citation: Cell Communication and Signaling 2023 21:238
Content type: Research Published on: 18 September 2023
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Estrogen-ERα signaling and DNA hypomethylation co-regulate expression of stem cell protein PIWIL1 in ERα-positive endometrial cancer cells
In the present study, we found that PIWIL1 mediated E2-stimulated cancer cell proliferation. In ERα-positive endometrial cancer cells, we demonstrated that estrogen-ERα signaling significantly up-regulated the ex...
Authors: Zheng Chen, Hua-Jing Yang, Qin Lin, Min-Jiao Zhu, Ying-Ying Yu, Xiao-Ying He and Xiao-Ping Wan
Citation: Cell Communication and Signaling 2020 18:84
Content type: Research Published on: 5 June 2020
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Swiprosin 1 – regulator of proximal BCR signaling
Authors: C Kroczek, C Lang, L Nitschke, A Elter, S Brachs, HM Jäck and D Mielenz
Citation: Cell Communication and Signaling 2009 7(Suppl 1):A79
Content type: Meeting abstract Published on: 26 February 2009
This article is part of a Supplement: Volume 7 Supplement 1
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Proteomic identification of the tyrosine phosphatase SHP1 as a novel LMP1 interaction partner, which mediates autoregulation of LMP1 signaling
Authors: J Griese, T Knoefel, H Kutz, SM Feller and A Kieser
Citation: Cell Communication and Signaling 2009 7(Suppl 1):A45
Content type: Meeting abstract Published on: 26 February 2009
This article is part of a Supplement: Volume 7 Supplement 1
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CCM signaling complex (CSC) couples both classic and non-classic Progesterone receptor signaling
Breast cancer, the most diagnosed cancer, remains the second leading cause of cancer death in the United States, and excessive Progesterone (PRG) or Mifepristone (MIF) exposure may be at an increased risk for ...
Authors: Johnathan Abou-Fadel, Xiaoting Jiang, Brian Grajeda, Akhil Padarti, Cameron C. Ellis, Esmeralda Flores, Alyssa-Marie D. Cailing-De La O and Jun Zhang
Citation: Cell Communication and Signaling 2022 20:120
Content type: Research Published on: 15 August 2022
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Ephs in cancer progression: complexity and context-dependent nature in signaling, angiogenesis and immunity
Eph receptors constitute the largest family of receptor tyrosine kinases, comprising 14 distinct members classified into two subgroups: EphAs and EphBs.. Despite their essential functions in normal physiological ...
Authors: Xiaoting Guo, Yanyi Yang, Jingqun Tang and Juanjuan Xiang
Citation: Cell Communication and Signaling 2024 22:299
Content type: Review Published on: 29 May 2024
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Signaling controversy and future therapeutical perspectives of targeting sphingolipid network in cancer immune editing and resistance to tumor necrosis factor-α immunotherapy
Anticancer immune surveillance and immunotherapies trigger activation of cytotoxic cytokine signaling, including tumor necrosis factor-α (TNF- ... cytokine TNF-α may be secreted by stromal cells, tumor-associated...
Authors: Olga A. Sukocheva, Margarita E. Neganova, Yulia Aleksandrova, Jack T. Burcher, Elena Chugunova, Ruitai Fan, Edmund Tse, Gautam Sethi, Anupam Bishayee and Junqi Liu
Citation: Cell Communication and Signaling 2024 22:251
Content type: Review Published on: 2 May 2024
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Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling
Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways...
Authors: Shivangi Pande, Xuehui Yang and Robert Friesel
Citation: Cell Communication and Signaling 2021 19:6
Content type: Review Published on: 12 January 2021
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TRIM3 facilitates estrogen signaling and modulates breast cancer cell progression
TRIM3 and ER alpha protein expression levels were measured by western blotting, while the mRNA levels of ER alpha target genes were measured by RT–PCR. A CCK-8 assay was used to measure cell viability. RNA sequen...
Authors: Ting Zhuang, Beibei Wang, Xiaojing Tan, Le Wu, Xin Li, Zhongbo Li, Yuqing Cai, Rongrong Fan, Xiao Yang, Chenmiao Zhang, Yan Xia, Zhiguo Niu, Bingtian Liu, Qi Cao, Yinlu Ding, Zhipeng Zhou…
Citation: Cell Communication and Signaling 2022 20:45
Content type: Research Published on: 7 April 2022
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FTO facilitates cancer metastasis by modifying the m6A level of FAP to induce integrin/FAK signaling in non-small cell lung cancer
FTO was upregulated and predicted poor prognosis in patients with NSCLC. FTO promoted cell migration and invasion in NSCLC, and the...6A level of FAP in a YTHDF2-dependent manner. Moreover, FTO-mediated metastasi...
Authors: Lirong Gao, Anqi Wang, Yuling Chen, Xin Cai, Yue Li, Jian Zhao, Yang Zhang, Weijie Zhang, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu and Jian-an Huang
Citation: Cell Communication and Signaling 2023 21:311
Content type: Research Published on: 2 November 2023
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Signaling, cancer cell plasticity, and intratumor heterogeneity
Cancer’s complexity is in part due to the presence of intratumor heterogeneity and the dynamic nature of cancer cell plasticity, which create substantial obstacles in effective ... from the existence of diverse p...
Authors: Marco Cordani, Ilaria Dando, Giulia Ambrosini and Pedro González-Menéndez
Citation: Cell Communication and Signaling 2024 22:255
Content type: Editorial Published on: 3 May 2024
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B cell antigen receptor-induced activation of an IRAK4-dependent signaling pathway revealed by a MALT1-IRAK4 double knockout mouse model
The B cell antigen receptor (BCR) and pathogen recognition ... , act in concert to control adaptive B cell responses. However, little is known about the signaling pathways that integrate BCR activation with intri...
Authors: Almut Dufner and Wolfgang W Schamel
Citation: Cell Communication and Signaling 2011 9:6
Content type: Research Published on: 11 March 2011
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Wnt signaling regulates chemokine production and cell migration of circulating human monocytes
The β-catenin dependent canonical Wnt signaling pathway plays a crucial role in maintaining normal homeostasis. However, when dysregulated, Wnt signaling is closely associated with various pathological conditi...
Authors: Natalie Zelikson, Shaina Ben, Michal Caspi, Raneen Tarabe, Yonatan Shaleve, Yael Pri-Paz Basson, Oshrat Tayer-Shifman, Elad Goldberg, Shaye Kivity and Rina Rosin-Arbesfeld
Citation: Cell Communication and Signaling 2024 22:229
Content type: Research Published on: 16 April 2024
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Tumor-associated macrophages promote epithelial–mesenchymal transition and the cancer stem cell properties in triple-negative breast cancer through CCL2/AKT/β-catenin signaling
Clinically, we observed a high infiltration of M2-like tumor-associated macrophages in TNBC tissues and confirmed that TAMs were associated with unfavorable prognosis in TNBC patients. Moreover, we found that co...
Authors: Xiangzhou Chen, Mingqiang Yang, Jiang Yin, Pan Li, Shanshan Zeng, Guopei Zheng, Zhimin He, Hao Liu, Qian Wang, Fan Zhang and Danyang Chen
Citation: Cell Communication and Signaling 2022 20:92
Content type: Research Published on: 17 June 2022
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Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma
Lipopolysaccharide served as a tumor promotor in ESCC by inducing cancer cell stemness through the activation of a LPS-TET3-HOXB2 signaling axis, which might provide a novel therapeutic...
Authors: Fengkai Xu, Zhonghe Liu, Ronghua Liu, Chunlai Lu, Lin Wang, Wei Mao, Qiaoliang Zhu, Huankai Shou, Kunpeng Zhang, Yin Li, Yiwei Chu, Jie Gu and Di Ge
Citation: Cell Communication and Signaling 2020 18:17
Content type: Research Published on: 3 February 2020
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